Pure Natural Apple Skin Extract 95% 98% Phlorizin Powder CAS 60-81-1

Pure Natural Apple Skin Extract 95% 98% Phlorizin Powder CAS 60-81-1

Phlorizin (also known as phloridzin) is a naturally occurring dihydrochalcone, a type of phenolic compound, primarily found in the bark and leaves of apple, pear, and other fruit trees. It was first isolated by French chemists in 1835 and has served as a significant tool in physiological and pharmacological research for over a century, playing a pivotal role in the understanding of diabetes and glucose metabolism.

Studies suggest that phlorizin possesses antioxidant, anti-inflammatory, and antimicrobial properties. A comprehensive 2025 study also provided mechanistic insights into its antidiarrheal action, identifying its potential to modulate inflammatory pathways (TLR4/NF-κB, PI3K/AKT) and exert antispasmodic effects.